Com gens tan semblants generen morfologies tan diverses? El paper clau de la genètica del desenvolupament i la genòmica comparada en la visió darwiniana de l'evolució

Authors

  • Jaume Baguñà Monjo

Abstract

Since Darwin (and Wallace) put forward the theory of evolution by natural selection, embryonic development and morphological evolution experienced, except for an early sunny spell, an absolute disregard to each other. Since the 1970s, Molecular Biology, and namely Developmental Genetics, Comparative Genomics and, later on, Evo-Devo, have changed for ever this odd situation. Embryonic development is controlled by genes and genetic changes are the base of morphological evolution. Moreover, at variance to cannonical evolutionary thinking, genes are similar in class and number among animals, are functionally equivalent, and are expressed at multiple places and times along development. The conservation of genes and proteins requires that morphological variation stems from cis-regulatory changes controlling when and where genes are expressed. The analysis of these regulatory regions, how they interconnect forming complex gene regulatory networks, and how they evolve in time to account for morphological variation represent a new paradigm to set up a new genetic theory of morphological evolution. Interestingly, this new paradigm falls closer to Darwins unity of type with modification than to some basic postulates of the neodarwinian Modern Synthesis.

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Published

2009-04-22