Biomarcadors de diagnòstic, pronòstic i predicció de resposta a tractaments oncològics

Authors

  • Marina Rigau
  • Mireia Olivan
  • Marta Llauradó
  • Eva Colás
  • Andreas Doll
  • Jaume Reventós i Puigjaner

Abstract

Better biomarkers are urgently needed to improve diagnosis, prognosis, and targeted intherapy across a wide range of diseases. Currently, scientists are moving forward to solve this problem. New developments in research help to discover many more biomarkers than ever before. However, although the number of articles that have been published in this area is increasing, only few biomarkers have been implemented in the clinical practice. This is mainly due to two reasons: biomarkers fail to meet the demands of the clinic; and false discoveries fail during the long way that represents the validation phases. The new biomarker pipeline, which currently includes new phases in the middle of the process, has significantly increased the percentage of success. In other words, the chances that the new findings are incorporated into routine clinical practice and improve the patient care are higher than before. This improvement in diagnosis, prognosis and targeted therapy, which is increasingly more specific for each patient who suffers a certain disease, brings us step by step closer to what is known as personalized medicine.

Published

2014-02-27