Usos de biomaterials i cèl·lules en regeneració de cartílag articular Authors Joaquim Vives Francesc Gòdia i Casablancas Abstract Many tissues in the body (including skin, blood and bone) can undergo self-repair to varying extents. However, injuries beyond the reparative threshold may benefit from therapeutic interventions to facilitate healing. The gold standard for many of these treatment strategies involves the use of autografts, but harvesting healthy tissue from other sites within the body is typically constrained by donor site morbidity and limited supply. To address this demand for donor tissue, tissue engineering has been recognised as an alternative therapeutic option, since it involves not only the use of biomaterials, but also cells and bioactive factors in various combinations to facilitate the regeneration of lost or injured tissue. This chapter focuses on cartilage tissue engineering as an example of the potential that novel biomaterials hold in regenerative medicine. Articular cartilage injuries are common in humans and are difficult to manage with current treatment options. The combination of novel biomaterials and expanded progenitor cells provide a source of therapeutic and immunologically compatible medicines that can be of interest in regenerative medicine. Downloads Text complet (Català) Published 2014-02-26 Issue 64, 2013 : Les malalties del segle XXI / Jordi Barquinero i Jaume Reventós, editors Section Articles License The intellectual property of the articles belongs to the respective authors. At the time of submitting the articles to Treballs de la Societat Catalana de Biologia, authors accept the following terms: — Authors assign to the SCB (a subsidiary of the Institut d’Estudis Catalans) the rights of reproduction, public communication (including communication through social networks) and distribution of the articles submitted for publication to Treballs de la Societat Catalana de Biologia, in any form and medium, including digital platforms. The Publications Committee reserves the right to accept or refuse submitted articles and the right to make any editorial changes it deems appropriate. If the suggested changes are accepted by authors, they should re-submit the article with such changes. — Authors answer to the SCB for the authorship and originality of submitted articles. In other words, authors assure that submitted articles do not contain fragments of works by other authors or fragments of their own previously published works; that the content of articles is original, and that the copyright of third parties is not infringed upon. Authors accept this responsibility and undertake to hold harmless the SCB for any loss or damage resulting from non-compliance with this obligation. Furthermore, they should include a statement in articles submitted to the journal regarding their responsibility for the content of the articles. — Authors are responsible for obtaining permission for the reproduction of all graphic material included in articles, and they should moreover ensure that images, videos, etc., have been created with the consent of the individuals appearing in them, and that material belonging to third parties is clearly identified and acknowledged as such within the text. Likewise, authors should provide the respective consents and authorisations to the SCB when submitting articles. — The SCB is exempt from any liability arising from the possible infringement of intellectual property rights by authors. In all cases, it undertakes to publish corrections, clarifications, retractions and apologies, if necessary. — Unless otherwise stated in the text or in the graphic material, the contents published in the journal are subject to an Attribution - NonCommercial - NoDerivs 3.0 Spain (by-nc-nd) license from Creative Commons, the full text of which may be consulted at https://creativecommons.org/licenses/by-nc-nd/3.0/es/deed.en. Therefore, the general public is authorised to reproduce, distribute and communicate articles as long as their authorship and publishing entity are acknowledged, and no commercial use is made of them nor derivative work produced from them. — The journal is not responsible for the ideas and opinions expressed by the authors of published articles.
