Macròlids: mecanismes d'acció i de resistència

Authors

  • Yolanda Sáenz
  • Aránzazu Portillo
  • Carmen Torres

Abstract

Macrolides are agents described by first time in the 50s. These agents are extensively used in the infections by gram-positive microorganisms. They act in the ribosome, by means of a reversible union with the 50S subunit. Currently we know different resistance mechanisms, and those include target modification, antibiotic inactivation, efflux pumps or impermeability.

Published

2006-02-01

Issue

Section

Principals grups d'agents antibacterians