Tuberculosis: A silent pandemic

Authors

Keywords:

Mycobacterium tuberculosis, sanatorium, artificial pneumothorax, Jaume Ferran, Ravetllat-Pla, BCG.

Abstract

Mycobacterium tuberculosis is a bacterium that has sacrificed its growth rate to wrap itself in an external membrane of mycolic acids and this has allowed it to survive protist predation and to establish a balance with macrophages. It specialized in a subclinical human parasitosis until it broke with the Neolithic culture and the exploitation of the majority, weakening their immune system, and reached its zenith in the Industrial Revolution. Tuberculosis, until then masked by other more explosive pandemics, silently emerged, confused as a hereditary disease, with Romanticism – a cultural movement that exalted the physical appearance of the sick – as its backdrop. Subsequently, thanks to the research of Robert Koch, tuberculosis was found to be the most devastating infectious disease. To deal with it, sanatorium therapy was consolidated and treatment with tuberculins and pneumothorax began. Likewise, vaccines and serotherapies were designed, and Catalan scientists came to play an important role in this field. With the advent of chemotherapy, it seemed that the pandemic would be controlled in the year 2000, but the difficulty in diagnosis, the AIDS epidemic, globalization and the appearance of resistances dashed the forecast, making tuberculosis a silent and uncontrollable pandemic once again.

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