Advanced devices for clinical nanodiagnostics

Authors

  • M. Carmen Estévez Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC, CIBER-BBN i BIST.
  • Laura M. Lechuga

Keywords:

early diagnosis, optical biosensors, point-of-care, biomarkers, nanomedicine.

Abstract

Advanced diagnostics (fast, accurate, non-invasive and portable) has become a key area in the field of nanomedicine, as it is the crucial first step to establish the disease and later on, for the therapy follow-up. Forthcoming novel analytical techniques will provide a fast, precise and reliable detection in early stages of a disease, requiring a low volume of patient’s sample (ideally a simple drop of sample), which will result in a noticeable social an economic impact. New diagnostic technologies ingeniously merge physical principles at the nanoscale with the use of highly selective biological receptors towards specific biomarkers related to particular clinical conditions or diseases. In this review we describe the state-of-of-the-art and future perspectives in the area of nanodiagnostics, in particular in the field of point-of-care devices for early and decentralized diagnosis: We especially emphasize those based on optical detection, as they currently show increasing potential and excellent properties for this purpose.

Keywords: early diagnosis, optical biosensors, point-of-care, biomarkers, nanomedicine.

Author Biographies

M. Carmen Estévez, Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC, CIBER-BBN i BIST.

Grup de Nanobiosensors i Aplicacions Bioanalítiques (Grup NanoB2A), Catalan Institute of Nanoscience
and Nanotechnology (ICN2), CSIC, CIBER-BBN i BIST.

Laura M. Lechuga

Grup NanoB2A, Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC, CIBER-BBN i BIST, 08193 Bellaterra, Barcelona. 

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Issue

Vol. 69 (2019)

Section

Destacats de recerca

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