Nuclear magnetic resonance (NMR) spectroscopy

Authors

  • Margarida Gairí Centres Científics i Tecnològics, Universitat de Barcelona
  • Miguel Feliz Centres Científics i Tecnològics, Universitat de Barcelona
  • Miquel Pons Laboratori de RMN de Biomolècules, Departament de Química Orgànica, Universitat de Barcelona

Keywords:

food quality control, metabolomics, protein structure and dynamics, drug discovery.

Abstract

NMR has become a powerful technique in biomedicine and biotechnology because of its ability to provide molecular information at atomic level. Among its many applications, we highlight its use for natural products characterization and the identification and quantification of individual components of complex mixtures in the pharmaceutical or food industries. NMR is a potent tool in medical diagnosis as well. Body images obtained through nuclear magnetic resonance imaging (NMRI) inform of the presence of tumours or injuries, and metabolites can be identified as specific disease-related biomarkers. In addition, NMR provides advantages in determining the structure, dynamics and function of drug targets such as proteins, and it can characterize drug-target interactions, which are critical to the drug discovery process.

Keywords: food quality control, metabolomics, protein structure and
dynamics, drug discovery.

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Issue

Vol. 66 (2015)

Section

Destacats de recerca

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