Immunotherapy: a classic concept with many new developments. Two specific examples: biologics and antitumour immunotherapy

Authors

  • Manel Juan Servei d’Immunologia, Centre de Diagnòstic Biomèdic, Hospital Clínic. Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)
  • Miguel Caballero Baños Servei d’Immunologia, Centre de Diagnòstic Biomèdic, Hospital Clínic. Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)
  • E. Azucena González Servei d’Immunologia, Centre de Diagnòstic Biomèdic, Hospital Clínic. Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)
  • Jordi Yagüe Servei d’Immunologia, Centre de Diagnòstic Biomèdic, Hospital Clínic. Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)

Keywords:

immunotherapy, biologics, cell therapy, antitumor.

Abstract

From the induction of immunological memory with anti-infectious vaccines through cell and gene immunotherapy to tumour treatments, the range of potential therapies stemming from modulation of the immune system is one of the most promising areas of immunology-based knowledge. Developments are constant and the results obtained during the early 21st century have placed immunotherapy among the areas with the greatest potential for clinical treatment. In this review, we focus on some of the biggest developments in treatment based on biological drugs (mainly antibodies) and, particularly, the progress made in the treatment of cancer by manipulating immune responses against tumour.

Key words: immunotherapy, biologics, cell therapy, antitumor.

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Issue

Vol. 65 (2014)

Section

Destacats de recerca

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