In quest of new drugs: the case of some antiretrovirals

Authors

  • Josep Font Universitat Autònoma de Barcelona. Departament de Química
  • Ramon Alibés Universitat Autònoma de Barcelona. Departament de Química
  • Félix Busqué Universitat Autònoma de Barcelona. Departament de Química
  • Jean Didier Maréchal Universitat Autònoma de Barcelona. Departament de Química

Keywords:

Medicinal chemistry, rational drug design, antiretroviral nucleosides, docking calculations.

Abstract

This paper gives a brief historical overview of the development of medicinal chemistry and especially of the rational design of new drugs. The specific example is presented of the use of the computer docking technique in the search for new small antiretroviral molecules.

Keywords: Medicinal chemistry, rational drug design, antiretroviral nucleosides, docking calculations.

Downloads

Download data is not yet available.

Downloads

Issue

No. 12 (2013)

Section

Articles

License

The intellectual property of articles belongs to the respective authors.

On submitting articles for publication to the journal Revista de la Societat Catalana de Química, authors accept the following terms:

  1. Authors assign to Catalan Society of Chemistry (a subsidiary of Institut d’Estudis Catalans) the rights of reproduction, communication to the public and distribution of the articles submitted for publication to Revista de la Societat Catalana de Química.
  2. Authors answer to Catalan Society of Chemistry for the authorship and originality of submitted articles.
  3. Authors are responsible for obtaining permission for the reproduction of all graphic material included in articles.
  4. Catalan Society of Chemistry declines all liability for the possible infringement of intellectual property rights by authors.
  5. The contents published in the journal, unless otherwise stated in the text or in the graphic material, are subject to a Creative Commons Attribution-NonCommercial-NoDerivs (by-nc-nd) 3.0 Spain licence, the complete text of which may be found at  http://creativecommons.org/licenses/by-nc-nd/3.0/es/deed.en. Consequently, the general public is authorised to reproduce, distribute and communicate the work, provided that its authorship and the body publishing it are acknowledged, and that no commercial use and no derivative works are made of it.
  6. The journal is not responsible for the ideas and opinions expressed by the authors of the published articles.