La Cromatografia líquida en la separació d'enantiòmers Authors Biotza Gutiérrez Raquel Sancho Cristina Minguillón Abstract More than 150 years ago Pasteur performed the known separation of the sodium ammonium tartrate,1 thus marking the starting point in the era of modern stereochemistry while performing the first enantioseparation. Crystallization, applied to enantiomers or to their derivatives, and kinetic resolution procedures, often involving enzymes, have been the most used methods in the separation and purification of this kind of isomers for long time. Nevertheless, huge efforts have been addressed to the design of more efficient procedures leading to the separation of enantiomers. Nowadays, thirty years from the first studies on the subject, liquid chromatography using chiral stationary phases has been consolidated as the most efficient analytical methodology to control the enantiomeric content of a mixture of isomers, and one of the most versatile procedures for the production of chiral compounds as single enantiomers. Downloads Text complet (Català) Published 2011-01-12 Issue No. 9 (2010) Section Articles License The intellectual property of articles belongs to the respective authors. On submitting articles for publication to the journal Revista de la Societat Catalana de Química, authors accept the following terms:Authors assign to Catalan Society of Chemistry (a subsidiary of Institut d’Estudis Catalans) the rights of reproduction, communication to the public and distribution of the articles submitted for publication to Revista de la Societat Catalana de Química.Authors answer to Catalan Society of Chemistry for the authorship and originality of submitted articles.Authors are responsible for obtaining permission for the reproduction of all graphic material included in articles.Catalan Society of Chemistry declines all liability for the possible infringement of intellectual property rights by authors.The contents published in the journal, unless otherwise stated in the text or in the graphic material, are subject to a Creative Commons Attribution-NonCommercial-NoDerivs (by-nc-nd) 3.0 Spain licence, the complete text of which may be found at http://creativecommons.org/licenses/by-nc-nd/3.0/es/deed.en. Consequently, the general public is authorised to reproduce, distribute and communicate the work, provided that its authorship and the body publishing it are acknowledged, and that no commercial use and no derivative works are made of it.The journal is not responsible for the ideas and opinions expressed by the authors of the published articles.
