Celebrating the Nobel Prize in Chemistry 2020. CRISPR-Cas genome editing tools

Authors

  • Lluís Montoliu Centro Nacional de Biotecnología (CNB-CSIC), Madrid

Keywords:

Genetic editing, genome editing, gene editing, CRISPR-Cas9, nucleases, gene therapy.

Abstract

In early October of last year, the Swedish Academy of Sciences awarded the 2020 Nobel Prize in Chemistry to two scientists, the French researcher Emmanuelle Charpentier and the American biochemist Jennifer Doudna, for the development of a genome editing method. The whole scientific community immediately understood that the prize was being granted for the CRISPR-Cas tools, derived from prokaryotic systems which, under the same name, had been described by a researcher at the University of Alicante, Francis Mojica, who also coined the now famous acronym CRISPR.

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Author Biography

Lluís Montoliu, Centro Nacional de Biotecnología (CNB-CSIC), Madrid

Lluís Montoliu (Barcelona, 1963) és llicenciat (1986) i doctor (1990) en ciències biològiques per la Universitat de Barcelona. Actualment és investigador científic del CSIC al Centro Nacional de Biotecnología (CNB) a Madrid, des del 1997. Anteriorment va treballar a Heidelberg (Alemanya) (1991-1995) i a la Universitat Autònoma de Barcelona (1995-1996). També és investigador i membre del Consell Directiu del CIBERER (CIBER de Enfermedades Raras, de l’Instituto de Salud Carlos III, ISCIII), president del Comitè d’Ètica del CSIC i director del node espanyol de la plataforma europea EMMA/Infrafrontier (Arxiu Europeu de Ratolins Mutants). Al CNB lidera el seu laboratori sobre models animals de malalties, centrat en l’estudi de l’albinisme. Va ser pioner en la introducció de les eines CRISPR a Espanya en animals. Presideix dues societats internacionals científiques — la European Society for Pigment Cell Research (ESPCR) i l’Association for Responsible Research and Innovation in Genome Editing (ARRIGE)— i és membre de les juntes directives d’altres societats nacionals — la Sociedad Española de Bioquímica y Biología Molecular (SEBBM), la Sociedad Española de Genética (SEG)— i internacionals — la International Federation of Pigment Cell Societies (IFPCS). Més enllà de la recerca i l’ètica, li interessa molt la divulgació de la ciència.

Centro Nacional de Biotecnología (CNB-CSIC), Madrid

Centro de Investigación Biomédica en Red de Enfermedades Raras del Instituto de Salud Carlos III (CIBERER-ISCIII), Madrid

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Issue

No. 20 (2021)

Section

Articles

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