The elaboration of the concept of chemical substance throughout secondary education. From the properties of a substance to its composition and structure Authors Aureli Caamaño Institut d'Estudis Catalans, Societat Catalana de Química Keywords: Chemical substance, chemical specie, chemical entity, chemical structure, interaction. Abstract The concept of chemical substance is one of the basic concepts of the chemistry curriculum in secondary education. The construction of this concept is based on concepts such as homogeneity, characteristic property, chemical identity, elemental composition, structure and interaction. This article presents a proposal for the progression of learning of the concept of chemical substance by developing a series of macroscopic, mesoscopic, atomicomolecular and electronic models. Author Biography Aureli Caamaño, Institut d'Estudis Catalans, Societat Catalana de Química És doctor en química per la Universitat de Barcelona (UB) i graduat en humanitats per la Universitat Pompeu Fabra (UPF). Ha estat catedràtic de física i química de secundària i ha impartit nombrosos cursos de formació del professorat a Espanya i Llatinoamèrica. És coordinador i coautor del llibre Enseñar Química. De las sustancias a la reacción química i coeditor de les revistes Alambique i Educació Química EduQ. Downloads PDF (Català) Issue No. 28 (2021) Section Monografia: Substància química License The intellectual property of articles belongs to the respective authors.On submitting articles for publication to the journal Educació Química, authors accept the following terms:Authors assign to Societat Catalana de Química (a subsidiary of Institut d’Estudis Catalans) the rights of reproduction, communication to the public and distribution of the articles submitted for publication to Educació Química.Authors answer to Societat Catalana de Química for the authorship and originality of submitted articles.Authors are responsible for obtaining permission for the reproduction of all graphic material included in articles.Societat Catalana de Química declines all liability for the possible infringement of intellectual property rights by authors.The contents published in the journal, unless otherwise stated in the text or in the graphic material, are subject to a Creative Commons Attribution-NonCommercial-NoDerivs (by-nc-nd) 3.0 Spain licence, the complete text of which may be found at https://creativecommons.org/licenses/by-nc-nd/3.0/es/deed.en. Consequently, the general public is authorised to reproduce, distribute and communicate the work, provided that its authorship and the body publishing it are acknowledged, and that no commercial use and no derivative works are made of it.Educació Química is not responsible for the ideas and opinions expressed by the authors of the published articles.