Discovering new arene-catalyzed lithiations Authors Miguel Yus Institute of Organic Synthesis, University of Alacant Abstract Arene-catalyzed lithiation is a useful and versatile methodology that promotes lithiation processes under very mild reaction conditions. This report presents recent results in the application of this technology, mainly in the following fields: (a) intramolecular carbolithiation vs. ring-opening in lithiomethylcycloalkanes; (b) the generation of dilithium synthons as precursors of bicyclic and spiro ethers, major units in biological active natural products; (c) general deprotection of different oxygen-, sulfur-, and nitrogen-containing protected compounds under non-hydrolytic conditions; and (d) the preparation of nickel nanoparticles and their application in carbon-carbon and carbon-nitrogen bond formation reactions. Downloads PDF Issue Vol. 6 No. 2 (2010): International Year of Chemistry: Special Issue / Salvador Alegret, Guest Editor Section Research reviews License This work is subject, unless the contrary is indicated in the text, the photographs or in other illustrations, to an Attribution —Non-Commercial— No Derivative Works 3.0 Creative Commons License, the full text of which can be consulted at http://creativecommons.org/licenses/by-nc-nd/3.0/. You are free to share, copy, distribute and transmit the work provided that the author is credited and reuse of the material is restricted to non-commercial purposes only and that no derivative works are created from the original material.
