Novel 10-bp deletion in the translational attenuator of a constitutively expressed erm(A) gene from Staphylococcus epidermidis

Autores/as

  • Leticia Millán Department of Microbiology, Zaragoza University School of Medicine, Spain
  • Pilar Goñi Department of Microbiology, Zaragoza University School of Medicine, Spain
  • Paula Cerdá Department of Microbiology, Zaragoza University School of Medicine, Spain
  • M. Carmen Rubio Department of Microbiology, Zaragoza University School of Medicine, Spain Microbiology Service, Lozano Blesa University Clinic Hospital, Zaragoza, Spain
  • Rafael Gómez-Lus Department of Microbiology, Zaragoza University School of Medicine, Spain

Palabras clave:

Staphylococcus epidermidis, erm(A) regulatory region, deletions, macrolide, lincosamide, streptogramin B (MLSB) resistance

Resumen

Alterations in the erm(A) regulatory region of six clinical isolates of Staphylococcus epidermidis and one of Staphylococcus haemolyticus displaying a constitutive resistance phenotype were investigated. Anovel deletion of 10 bp with respect to the corresponding sequence of Tn554 was identified in the attenuator of a constitutively expressed erm(A) gene of one of the S. epidermidis isolates. Thus far, this is the smallest deletion conferring constitutive resistance in the translational attenuator of erm(A) in a naturally occurring S. epidermidis strain of human origin. [Int Microbiol 2007; 10(2):147-150]

Biografía del autor/a

Leticia Millán, Department of Microbiology, Zaragoza University School of Medicine, Spain

Department of Microbiology, Zaragoza University School of Medicine, Spain

Pilar Goñi, Department of Microbiology, Zaragoza University School of Medicine, Spain

Department of Microbiology, Zaragoza University School of Medicine, Spain

Paula Cerdá, Department of Microbiology, Zaragoza University School of Medicine, Spain

Department of Microbiology, Zaragoza University School of Medicine, Spain

M. Carmen Rubio, Department of Microbiology, Zaragoza University School of Medicine, Spain Microbiology Service, Lozano Blesa University Clinic Hospital, Zaragoza, Spain

Department of Microbiology, Zaragoza University School of Medicine, Spain Microbiology Service, Lozano Blesa University Clinic Hospital, Zaragoza, Spain

Rafael Gómez-Lus, Department of Microbiology, Zaragoza University School of Medicine, Spain

Department of Microbiology, Zaragoza University School of Medicine, Spain

Descargas

Publicado

2010-01-26

Número

Vol. 10 Núm. 2 (2007)

Sección

Research Notes

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