Molecular characterization of InJR06, a class 1 integron located in a conjugative plasmid of Salmonella enterica ser. Typhimurium

Autors/ores

  • José Di Conza Faculty of Biochemistry & Biological Sciences (UNL), Santa Fe, Argentina
  • Juan A. Ayala Center for Molecular Biology “Severo Ochoa” (CSIC-UAM) Cantoblanco, Madrid, Spain
  • Ayelén Porto Faculty of Biochemistry & Biological Sciences (UNL), Santa Fe, Argentina
  • Marta Mollerach Faculty of Pharmacy and Biochemistry (UBA), Buenos Aires, Argentina
  • Gabriel Gutkind Faculty of Pharmacy and Biochemistry (UBA), Buenos Aires, Argentina

Paraules clau:

Salmonella Typhimurium, class 1 integron, aminoglycoside, ant(3´´)-Ia, gene cassette

Resum

The presence of class 1, 2, and 3 integrons was investigated in four pediatric isolates of Salmonella enterica ser. Typhimurium (S. Typhimurium). A class 1 integron was detected in one S. Typhimurium strain, the only one that also showed resistance to various aminoglycoside antibiotics. This integron, called InJR06, and the aminoglycoside resistance determinants were located in pS06, a large (≥55 kb) conjugative plasmid. Asingle mobile cassette (encoding the aminoglycoside adenylyltransferase ANT(3´´)-Ia) was detected in the variable region of InJR06, while the architecture of the attI1 and attC sites was conserved. [Int Microbiol 2005; 8(4):287-290]

Descàrregues

Publicat

2010-02-26

Número

Vol. 8 Núm. 4 (2005)

Secció

Research Notes

Llicència

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