The sophisticated survival strategies of the pathogen Listeria monocytogenes

Autors/ores

  • Jürgen Wehland Gesellschaft für Biotechnologische Forschung (GBF), Braunschweig, Germany
  • Uwe D. Carl Gesellschaft für Biotechnologische Forschung (GBF), Braunschweig, Germany

Paraules clau:

Listeria monocytogenes, ActA, profilin, Ena/VASP family, actinbased motility

Resum

The function of the ActA protein of Listeria monocytogenes has been partially elucidated. These results illustrate the sophistication with which intracellular pathogens like Listeria use the host cell to their advantage, and have provided new insights into some of the molecular mechanisms of complex cell functions such as actin-promoted cell motility. The clarification of these processes is of fundamental importance not only for understanding elementary processes such as development and growth, but also for the treatment of both diseases caused by cytopathogenic bacteria such as Listeria and pathophysiological processes arising from disorders in cell motility and cell adhesion.

Descàrregues

Publicat

2010-03-18

Número

Vol. 1 Núm. 1 (1998)

Secció

Articles

Llicència

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