Novel 10-bp deletion in the translational attenuator of a constitutively expressed erm(A) gene from Staphylococcus epidermidis Authors Leticia Millán Department of Microbiology, Zaragoza University School of Medicine, Spain Pilar Goñi Department of Microbiology, Zaragoza University School of Medicine, Spain Paula Cerdá Department of Microbiology, Zaragoza University School of Medicine, Spain M. Carmen Rubio Department of Microbiology, Zaragoza University School of Medicine, Spain Microbiology Service, Lozano Blesa University Clinic Hospital, Zaragoza, Spain Rafael Gómez-Lus Department of Microbiology, Zaragoza University School of Medicine, Spain Keywords: Staphylococcus epidermidis, erm(A) regulatory region, deletions, macrolide, lincosamide, streptogramin B (MLSB) resistance Abstract Alterations in the erm(A) regulatory region of six clinical isolates of Staphylococcus epidermidis and one of Staphylococcus haemolyticus displaying a constitutive resistance phenotype were investigated. Anovel deletion of 10 bp with respect to the corresponding sequence of Tn554 was identified in the attenuator of a constitutively expressed erm(A) gene of one of the S. epidermidis isolates. Thus far, this is the smallest deletion conferring constitutive resistance in the translational attenuator of erm(A) in a naturally occurring S. epidermidis strain of human origin. [Int Microbiol 2007; 10(2):147-150] Author Biographies Leticia Millán, Department of Microbiology, Zaragoza University School of Medicine, Spain Department of Microbiology, Zaragoza University School of Medicine, Spain Pilar Goñi, Department of Microbiology, Zaragoza University School of Medicine, Spain Department of Microbiology, Zaragoza University School of Medicine, Spain Paula Cerdá, Department of Microbiology, Zaragoza University School of Medicine, Spain Department of Microbiology, Zaragoza University School of Medicine, Spain M. Carmen Rubio, Department of Microbiology, Zaragoza University School of Medicine, Spain Microbiology Service, Lozano Blesa University Clinic Hospital, Zaragoza, Spain Department of Microbiology, Zaragoza University School of Medicine, Spain Microbiology Service, Lozano Blesa University Clinic Hospital, Zaragoza, Spain Rafael Gómez-Lus, Department of Microbiology, Zaragoza University School of Medicine, Spain Department of Microbiology, Zaragoza University School of Medicine, Spain Downloads PDF Published 2010-01-26 Issue Vol. 10 No. 2 (2007) Section Research Notes License Submission of a manuscript to International Microbiology implies: that the work described has not been published before, including publication in the World Wide Web (except in the form of an Abstract or as part of a published lecture, review, or thesis); that it is not under consideration for publication elsewhere; that all the coauthors have agreed to its publication. The corresponding author signs for and accepts responsability for releasing this material and will act on behalf of any and all coauthors regarding the editorial review and publication process.If an article is accepted for publication in International Microbiology, the authors (or other copyright holder) must transfer to the journal the right–not exclusive–to reproduce and distribute the article including reprints, translations, photographic reproductions, microform, electronic form (offline, online) or any other reproductions of similar nature. Nevertheless, all article in International Microbiology will be available on the Internet to any reader at no cost. The journal allows users to freely download, copy, print, distribute, search, and link to the full text of any article, provided the authorship and source of the published article is cited. The copyright owner's consent does not include copying for new works, or resale. In these cases, the specific written permission of International Microbiology must first be obtained.Authors are requested to create a link to the published article on the journal's website. The link must be accompanied by the following text: "The original publication is available on LINK at <http://www.im.microbios.org>. Please use the appropiate URL for the article in LINK. Articles disseminated via LINK are indexed, abstracted, and referenced by many abstracting and information services, bibliographic networks, subscription agencies, library networks, and consortia.
