Molecular evolution in yeast of biotechnological interest Authors Amparo Querol Departamento de Biotecnología, Instituto de Agroquímica y Tecnología de Alimentos, CSIC, Burjassot, Valencia, Spain Carmela Belloch Colección Española de Cultivos Tipo (CECT), Universitat de Valencia, Burjassot, Valencia, Spain María Teresa Fernández-Espinar Departamento de Biotecnología, Instituto de Agroquímica y Tecnología de Alimentos, CSIC, Burjassot, Valencia, Spain Eladio Barrio Institut Cavanilles de Biodiversitat i Biologia Evolutiva; and Departament de Genètica, Universitat de València, Campus de Paterna, Valencia, Spain Keywords: yeasts biotechnology, adaptive evolution, molecular phylogeny Abstract The importance of yeast in the food and beverage industries was only realized about 1860, when the role of these organisms in food manufacture became evident. Since they grow on a wide range of substrates and can tolerate extreme physicochemical conditions, yeasts, especially the genera Saccharomyces and Kluyveromyces, have been applied to many industrial processes, Industrial strains of these genera are highly specialized organisms that have evolved to utilize a range of environments and ecological niches to their full potential. This adaptation is called “domestication”. This review describes the phylogenetic relationships among Saccharomyces and Kluyveromyces species and the different mechanisms involved in the adaptive evolution of industrial yeast strains. Downloads PDF Published 2010-03-08 Issue Vol. 6 No. 3 (2003) Section Review Articles License Submission of a manuscript to International Microbiology implies: that the work described has not been published before, including publication in the World Wide Web (except in the form of an Abstract or as part of a published lecture, review, or thesis); that it is not under consideration for publication elsewhere; that all the coauthors have agreed to its publication. The corresponding author signs for and accepts responsability for releasing this material and will act on behalf of any and all coauthors regarding the editorial review and publication process.If an article is accepted for publication in International Microbiology, the authors (or other copyright holder) must transfer to the journal the right–not exclusive–to reproduce and distribute the article including reprints, translations, photographic reproductions, microform, electronic form (offline, online) or any other reproductions of similar nature. Nevertheless, all article in International Microbiology will be available on the Internet to any reader at no cost. The journal allows users to freely download, copy, print, distribute, search, and link to the full text of any article, provided the authorship and source of the published article is cited. The copyright owner's consent does not include copying for new works, or resale. In these cases, the specific written permission of International Microbiology must first be obtained.Authors are requested to create a link to the published article on the journal's website. The link must be accompanied by the following text: "The original publication is available on LINK at <http://www.im.microbios.org>. Please use the appropiate URL for the article in LINK. Articles disseminated via LINK are indexed, abstracted, and referenced by many abstracting and information services, bibliographic networks, subscription agencies, library networks, and consortia.