HDL: A molecular view of the "classic" antiatherogenic lipoprotein Authors Vicent Ribas Francisco Blanco-Vaca Francesc González i Sastre Abstract HDL metabolism and its relationship to atherosclerosis is a complex topic, though notable advances have been made. First, HDL clearly has an anti-atherogenic action. Second, this action is due to some fraction/s containing apoA-I but not apoA-II. Third, some of the molecular mechanisms involved in two key anti-atherogenic functions of HDL have been defined: reverse cholesterol transport and prevention of LDL oxidative modification. These advances may permit the development of effective strategies, complementing those already available, for treating and preventing atherothrombotic cardiovascular diseases. Downloads Text complet Published 2003-08-01 Issue 2-2 Section Research reviews License This work is subject, unless the contrary is indicated in the text, the photographs or in other illustrations, to an Attribution —Non-Commercial— No Derivative Works 3.0 Creative Commons License, the full text of which can be consulted at http://creativecommons.org/licenses/by-nc-nd/3.0/. You are free to share, copy, distribute and transmit the work provided that the author is credited and reuse of the material is restricted to non-commercial purposes only and that no derivative works are created from the original material.
